"Can't save program!" message

[PhilOfPerth]

Sounds like a permission issue.  Honestly, you'd be better served to either move QB64 simply to drive C:, or to your User folder.  If you absolutely have to have it in Programs (x86), then set permission manually:

You could try the following on the folder that you have created under the Program Files (X86):

1) Go to your folder under C:\Program Files(x86).

2) Right click your folder and click on Properties.

3) Click on the Security tab. Then click on Advanced.

4) Under Permissions, click on Change permissions.

5) Click on Add and then on Select a Principal.

6) Under "Enter the object name to select (examples)", type Everyone and press Ok.

7) Under Basic permissions, click on Full control and then select Ok.

8) Press Apply and Ok. In your folder's properties window, click on Edit.

9) Click on Add and then enter Everyone.

10) Select Everyone in the list and then select Full control and press Ok.

I've moved the folder to now become C:/QB64PE and everything still works as before - links etc were intact - but still says Cannot save file. The settings had become Read Only again, and I've removed that, but no change.